Table 1

Baseline demographic and ICU variables of long-term ARDS survivors (n=138)

Not working prior to ARDS (n=71)Working prior to ARDS (n=67), stratified by post-ARDS outcome
All patients
(n=67)
Ever returned to work (n=45)Never returned to work (n=17)Retired or died (n=5)
Demographic variables*
 Age, median (IQR) (year)49 (40, 58)46 (39, 54)44 (36, 49)45 (41, 49)50 (40, 61)
 Male sex, n (%)32 (45%)42 (63%)31 (69%)9 (53%)2 (40%)
 White race, n (%)40 (56%)38 (57%)23 (51%)10 (59%)5 (100%)
 Full-time education, median (IQR) (year)12 (11, 14)12 (11, 14)12 (12, 16)12 (12, 14)12 (11, 14)
 Living at home before admission, n (%)66 (93%)65 (97%)44 (98%)16 (94%)5 (100%)
 Charlson Comorbidity Score, median (IQR)1 (1, 4)1 (0, 2)0 (0, 1)2 (1, 4)1 (1, 3)
 Functional Comorbidity Index, median (IQR)1 (1, 3)1 (0, 2)1 (0, 2)2 (0, 3)1 (1, 3)
Hospital variables
 Admission diagnosis
  Respiratory failure/pneumonia39 (55%)36 (54%)23 (51%)10 (59%)3 (60%)
  Sepsis (non-pulmonary)/infectious disease8 (11%)13 (19%)8 (18%)4 (24%)1 (20%)
  Trauma2 (3%)8 (12%)8 (18%)0 (0%)0 (0%)
  Gastrointestinal7 (10%)5 (7%)4 (9%)1 (6%)0 (0%)
  Other†15 (21%)5 (7%)2 (4%)2 (12%)1 (20%)
 APACHE II score, median (IQR)24 (19, 29)23 (18, 28)20 (17, 26)25 (20, 28)24 (19, 29)
 Mean daily SOFA score, median (IQR)5 (4, 7)5 (4, 7)4 (3, 5)5 (4, 8)5 (4, 7)
 Days with delirium, median (IQR)2 (1, 7)3 (1, 7)3 (1, 7)4 (1, 8)3 (1, 7)
 Days with coma, median (IQR)3 (1, 8)3 (1, 8)3 (1, 6)5 (3, 6)3 (1, 8)
 Days on mechanical ventilation, median (IQR)8 (5, 17)9 (5, 17)9 (6, 13)12 (7, 17)8 (5, 17)
 ICU LOS, median (IQR) (day)14 (8, 23)14 (9, 22)14 (11, 20)16 (12, 24)14 (8, 23)
 Hospital LOS, median (IQR) (day)23 (16, 45)23 (16, 35)21 (16, 28)32 (26, 37)23 (16, 45)
 Hospital discharge location
  Home31 (44%)30 (45%)24 (53%)6 (35%)0 (0%)
  Rehabilitation facility28 (39%)34 (51%)19 (42%)10 (59%)5 (100%)
  Long-term ventilator facility2 (3%)2 (3%)1 (2%)1 (6%)0 (0%)
  Nursing home8 (11%)0 (0%)0 (0%)0 (0%)0 (0%)
  Other hospital2 (3%)1 (1%)1 (2%)0 (0%)0 (0%)
  • *Missing data (n, %): full-time education (5 of 71 [7%] not working and 1 of 67 [1%] working).

  • †Among survivors not working before ARDS, ‘other’ diagnoses included neurological (n=1, 1%), cardiovascular (n=4, 6%), rheumatological/orthopaedic (n=1, 1%), endocrine (n=2, 3%), haematologic (n=2, 3%) and other (n=5, 7%). Among survivors working before ARDS, diagnoses included neurological (n=3, 4%), cardiovascular (n=1, 1%) and rheumatological/orthopaedic (n=1, 1%).

  • APACHE, Acute Physiology and Chronic Health Evaluation; ARDS, acute respiratory distress syndrome; ICU, intensive care unit; LOS, length of stay; SOFA, Sequential Organ Failure Assessment.