Baseline characteristics of the main study group (CF) and ancillary dataset (non-CF)
| Patients with CF (n=63; 24F) | Patients with non-CF bronchiectasis (n=15; 9F) | ||||
| Mean | 95% CI for the mean | Mean | 95% CI for the mean | ||
| Age | (year) | 29 | (27 to 31) | 62 | (55 to 68) |
| Height | (cm) | 172 | (170 to 174) | 167 | (163 to 170) |
| BMI | (kg/m2) | 21 | (21 to 22) | 25 | (22 to 27) |
| HRCT score | |||||
| Bhalla score | 14.4 | (13.0 to 15.8) | 14.6 | (12.7 to 16.5) | |
| Spirometry | |||||
| FEV1 | (%pred) | 66 | (61 to 71) | 65 | (59 to 71) |
| (Z score) | −5.4 | (−6.6 to −4.2) | −4.4 | (−5.5 to −3.4) | |
| FVC | (%pred) | 82 | (79 to 85) | 72 | (66 to 78) |
| (Z score) | −1.9 | (−2.3 to −1.5) | −2.9 | (−3.7 to −2.2) | |
| FEV1/FVC | (%) | 0.65 | (0.61 to 0.69) | 0.68 | (0.65 to 0.720 |
| (Z score) | −3.6 | (−4.4 to −2.8) | −1.7 | (−2.3 to −1.1) | |
| MBW | |||||
| LCI | (−) | 9.3 | (8.7 to 10.0) | 7.8 | (7.2 to 8.4) |
| (%pred) | 152 | (142 to 163) | 115 | (106 to 123) | |
| (Z score) | 5.0 | (4.1 to 5.8) | 1.6 | (0.5 to 2.6) | |
| Curv | (−) | 0.50 | (0.45 to 0.55) | 0.39 | (0.32 to 0.45) |
| (%pred) | 286 | (258 to 314) | 158 | (129 to 188) | |
| (Z score) | 4.6 | (3.9 to 5.3) | 1.7 | (0.9 to 2.5) | |
| Sacin* | (L−1) | 0.26 | (0.20 to 0.31) | 0.34 | (0.25 to 0.44) |
| (%pred) | 319 | (250 to 388) | 291 | (214 to 367) | |
| (Z score) | 3.4 | (2.4 to 4.3) | 3.5 | (2.3 to 4.7) | |
| Scond* | (L−1) | 0.15 | (0.13 to 0.16) | 0.14 | (0.10 to 0.17) |
| (%pred) | 416 | (364 to 467) | 271 | (211 to 332) | |
| (Z score) | 6.4 | (5.4 to 7.3) | 2.6 | (1.8 to 3.3) | |
BMI, body mass index; CF, cystic fibrosis; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; HRCT, high-resolution computed tomography; LCI, lung clearance index; MBW, multiple breath washout.