Changes in exercise capacity from baseline to 3 months: exploratory secondary analyses post intervention
| Control | Intervention | Mean difference | 95% CI | p Value | |||
| Baseline n=18 | Δ 3 months n=15 | Baseline n=15 | Δ 3 months n=14 | ||||
| DASI (AU) | 13.1 (5.2 to 28.7) | 2.8 (0 to 4.5) | 15.5 (10.3 to 31.2) | 8* (−2.8 to 14.5) | 5.62 | −0.63 to 11.86 | 0.08 |
| DASI (mL/min) estimated peak oxygen uptake | 15.1 (11.8 to 22.0) | 1.2 (0 to 1.9) | 16.2 (14.0 to 23.0) | 3.4* (−1.18 to 6.2) | 2.41 | −0.19 to 5.0 | 0.07 |
| STS (number of repetitions) | 19 (9 to 23) | 0 (−3 to 5) | 19 (16 to 23) | 5* (3.5 to 9.5) | 5.2† | 0.97 to 9.38 | 0.02† |
| TUAG (s) | 14.9 (10.6 to 28.7) | −2.3 (−8.4 to −0.9) | 14.0 (10.0 to 18.0) | −2.8* (−11.1 to 0.25) | 0.62 | −6.92 to 8.16 | 0.87 |
| 6MW distance (m) | 165 (100 to 288) | 20* (0 to 90) | 200 (100 to 320) | 60* (20 to 190) | 9.35† | 0.67 to 18.03 | 0.04† |
| MRC breathlessness scale | 4 (3 to 5) | −0.5 (−1 to 1) | 4 (3 to 4) | −1* (−2 to 0) | −0.98† | −1.87 to −0.08 | 0.03† |
Missing data at 3 months: control n=2, intervention n=2.
*Significant intragroup difference from baseline p<0.05.
†Parameters with significant difference between groups from baseline to 3 months in p value column, p<0.05.
DASI, Dukes Activity Status Index; MRC, Medical Research Council; STS, sit to-stand; TUAG, timed up and go; 6MWT, 6 min walk test