Demographics of patient cohorts commencing anti-fibrotic therapy
| Whole Group | Tolerant cohort | Intolerant cohort | P-value | Intolerant weight loss cohort | P-value | |
|---|---|---|---|---|---|---|
| No. of patients (n) | 137 | 84 | 53 | 14 | ||
| Mean age (SD), years | 72.3 (7.64) | 70.3 (7.63) | 75.2 (6.62) | 0.0003* | 77.9 (5.34) | 0.001* |
|
Mean starting FVC
% Predicted (SD) | 73.7 (15.3) | 73.1 (15.0) | 74.5 (15.5) | 0.61 | 70 (11.5) | 0.31 |
| Gender F:M% | 27 : 72 | 25 : 73 | 30 : 70 | 0.55 | 29 : 71 | 0.75 |
| Mortality at 12 months (no. of patients) | 25 | 12 | 13 | 0.17 | 1 (from intolerant cohort) | 0.69 |