Demographic details of subjects with BAL samples included for analysis compared with remainder of original birth cohort at recruitment
| Study subjects (n=48) | Remainder of birth cohort (n=94) | p Value (χ2) | |
|---|---|---|---|
| Male, n (%) | 25 (52%) | 38 (40%) | 0.19 |
| Mode of diagnosis | n=46 | n=87 | 0.54 |
| Newborn screening, n (%) | 33 (72%) | 65 (75%) | |
| Meconium ileus, n (%) | 11 (24%) | 16 (18%) | |
| Other clinical presentation, n (%) | 2 (4%) | 3 (3%) | |
| Family history, n (%) | 0 | 3 (3%) | |
| Pancreatic status at recruitment | n=48 | n=79 | 0.93 |
| Pancreatic insufficient, n (%) | 41 (85%) | 67 (85%) | |
| Pancreatic sufficient, n (%) | 7 (145%) | 12 (15%) | |
| CFTR genotype | n=47 | n=85 | 0.03 |
| P.Phe508del homozygous, n (%) | 32 (68%) | 38 (45%) | |
| P.Phe508del heterozygous, n (%) | 14 (30%) | 42 (49%) | |
| Other, n (%) | 1 (2%) | 5 (6%) |
BAL, bronchoalveolar lavage.