Clinical characteristics of patients included in the clusters resembling the ‘moderate airflow limitation, high BMI and cardiovascular comorbidities’ subtype
| Cohort | ICECOLDERIC | LEUVEN | PAC-COPD |
| n (% of the cohort) | 90 (22.3%) | 60 (10.9%) | 45 (13.2%) |
| FEV1 (%predicted) | 71.2 (6.3) | 50.6 (7.2) | 63.8 (4.1) |
| FEV1/FVC (%) | 63.3 (3.6) | 58.2 (6.7) | 65.8 (4.3) |
| FVC (%predicted) | 91.9 (10.6) | 68.7 (7.8) | 71.7 (4.7) |
| BMI (kg/m2) | 29.1 (6.0) | 30.1 (5.6) | 31.5 (3.5) |
| MMRC (0–4) | 1.3 (1.3) | 2.1 (0.9) | 1.4 (0.8) |
| Asthma, % | 1 | 0 | 64 |
| CVD, % | 21 | 45 | 31 |
Values are mean (SD) unless otherwise noted. Complete description of best NMI cluster solutions for each cohort are available in online supplementary tables 2–11.
BMI. body mass index; CVD, cardiovascular disease; MMRC, Modified Medical Research Council; NMI, normalised mutual information.