Baseline scan result | Quit smoking | Total | Univariable OR (95% CI) | Multivariable OR* (95% CI) | |
---|---|---|---|---|---|
Primary analysis† | |||||
T1 | Control group | 36 | 786 | –Reference– | –Reference– |
Negative result‡ | 26 | 340 | 1.73 (1.02 to 2.91) | 1.78 (1.04 to 3.05) | |
Additional investigation‡ | 48 | 416 | 2.72 (1.73 to 4.26) | 2.85 (1.79 to 4.53) | |
T2 | Control group | 79 | 775 | –Reference– | –Reference– |
Negative result‡ | 32 | 338 | 0.92 (0.60 to 1.42) | 0.90 (0.58 to 1.40) | |
Additional investigation‡ | 83 | 409 | 2.24 (1.60 to 3.14) | 2.29 (1.62 to 3.22) | |
Sensitivity analysis§ | |||||
T1 | Control group | 36 | 479 | –Reference– | –Reference– |
Negative result | 26 | 227 | 1.59 (0.94 to 2.71) | 1.61 (0.93 to 2.77) | |
Additional investigation‡ | 48 | 299 | 2.35 (1.49 to 3.72) | 2.46 (1.53 to 3.96) | |
T2 | Control group | 79 | 377 | –Reference– | –Reference– |
Negative result | 32 | 212 | 0.67 (0.43 to 1.05) | 0.65 (0.41 to 1.04) | |
Additional investigation‡ | 83 | 275 | 1.63 (1.14 to 2.33) | 1.66 (1.15 to 2.39) |
*Adjusted for T0 cancer distress, recruitment site, gender, age, marital group, deprivation and experience of lung cancer.
†Intention-to-treat (ITT) analyses with the imputed population.
‡One participant removed due to protocol deviation.
§Complete case analyses.