Table 4

Convergent validity testing: Spearman's rank correlation coefficients between scales from QOL-PCD and generic HRQOL measures (SNOT-20, SGRQ-C and SF-36)

SNOT-20SGRQ-C SF-36
Scales of QOL-PCDTotalSymptomsActivityImpactsPhysical functioningRolephysicalBodily painGeneral healthVitalitySocial functioningRole functioningMental healthTotal physical scoreTotal mental score
Physical0.51−0.83−0.78−0.85−0.740.830.790.540.790.650.620.490.460.840.37
Emotional−0.48−0.52−0.04−0.47−0.540.470.550.600.630.610.670.600.730.570.69
Treatment−0.61−0.67−0.61−0.54−0.650.540.670.780.660.540.500.540.380.710.36
Social−0.21−0.43−0.40−0.28−0.480.340.350.320.420.460.280.270.340.390.27
Role−0.60−0.80−0.73−0.67−0.780.730.840.680.790.690.720.440.470.860.43
Health−0.64−0.84−0.76−0.72−0.840.710.790.760.870.790.760.500.620.870.56
Vitality−0.46−0.63−0.67−0.49−0.590.590.560.600.720.750.520.430.390.690.43
Upper respiratory−0.60−0.39−0.31−0.31−0.390.360.510.540.480.350.420.370.390.480.35
Lower respiratory−0.53−0.72−0.69−0.61−0.690.590.690.580.750.670.590.430.490.690.49
Ear and hearing−0.57−0.47−0.40−0.36−0.490.510.490.460.660.550.510.390.460.560.47
  • We a priori hypothesised scales that would have stronger correlations (closer to 1 or −1); these correlations are shadowed grey.

  • HRQOL, health-related quality of life;

  • PCD, primary ciliary dyskinesia; QOL, quality of life; SF-36, Medical Outcome Survey Short Form-36 (higher score indicates better health status); SGRQ-C, St George Respiratory Questionnaire (higher score indicates worse HRQOL).