Clinical outcomes according to the presence of diaphragm dysfunction at switch to pressure support ventilation
| Diaphragm dysfunction defined as Ptr,stim <11 cm H2O | Diaphragm dysfunction defined as TFdi <29% | |||||
|---|---|---|---|---|---|---|
| Yes (n=67) | No (n=32) | p Value | Yes (n=61) | No (n=38) | p Value | |
| Length of ICU stay, days | 10 (6–16) | 6 (3–12) | 0.05 | 10 (6–17) | 6 (4–11) | 0.02 |
| Length of MV, days | 7 (5–11) | 4 (1–7) | 0.04 | 7 (5–12) | 5 (2–8) | 0.02 |
| ICU deaths, n (%) | 15 (22) | 2 (6) | 0.05 | 16 (26) | 1 (3) | 0.002 |
| Hospital deaths, n (%) | 18 (27) | 3 (9) | 0.05 | 19 (31) | 2 (5) | 0.002 |
| Remaining days of MV after measurement, days | 3 (1–5) | 0 (0–1) | 0.04 | 2 (1–5) | 0 (0–3) | 0.04 |
Analyses were performed on the subset of patients with a measurement performed at the time of switch to PSV (n=99).
Continuous variables are presented as median (IQR) and categorical variables are expressed as absolute (relative) frequency.
ICU, intensive care unit; MV, mechanical ventilation; PSV, pressure support ventilation; Ptr,stim, twitch pressure in response to bilateral phrenic nerve stimulation; TFdi, thickening fraction of the diaphragm.