Bronchodilator responses at 18 years in various groups—changes in FEV1 post salbutamol
| Continuous mean (SD) | Mean difference (95% CI) | >12% increase % (n/N) | OR (95% CI) | ||
|---|---|---|---|---|---|
| Both groups | |||||
| Preterm | Control | Preterm | Control | ||
| 6.3 (7.2) n=203 | 3.7 (5.5) n=151 | 2.6 (1.3 to 4.0) p<0.001 | 12% [25/203] | 5% [7/151] | 2.89 (1.22 to 6.85) p=0.013 |
| Preterm group only | |||||
| BPD | No BPD | BPD | No BPD | ||
| 8.4 (7.5) n=75 | 5.1 (6.8) n=128 | 3.3 (1.2 to 5.3) p=0.002 | 21% [16/75] | 7% [9/128] | 3.58 (1.50 to 8.60) p=0.003 |
| Smokers | Non-smokers | Smokers | Non-smokers | ||
| 7.3 (9.0) n=35 | 6.2 (6.8) n=164 | 1.1 (−1.5 to 3.8) p=0.41 | 17% [6/35] | 12% [19/164] | 1.58 (0.58 to 4.30) p=0.37 |
BPD, bronchopulmonary dysplasia.