Prognostic scores and their components
Measured indices | Study population and primary outcome | AUROC for death or readmission48 | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Age | BMI | Comorbidity* | Dyspnoea† | Airflow obstruction‡ | Exacerbations§ | Severe exacerbations¶ | Smoking status | Length of stay | Acuity** | ED visits last 6 months | COPD specific? | Stable-state or exacerbating at inclusion | Outpatients or admitted patients | Primary outcome | ||
ADO5 | √ | √ | √ | √ | Both | Both | Death | 0.58 | ||||||||
BODEX6 | √ | √ | √ | √ | √ | Stable | Outpatients | Death | 0.61 | |||||||
CODEX4†† | √ | √ | √ | √ | √ | √ | AECOPD | Mostly admitted | Death or readmission | 0.67 | ||||||
DOSE7 | √ | √ | √ | √ | √ | Unclear | Outpatients | Health status‡‡ | 0.64 | |||||||
LACE8 | √ | √ | √ | √ | X | N/A | Admitted | Death or readmission | 0.68§§ |
*Charlson Comorbidity Index.
†mMRC dyspnoea score.
‡FEV1 %predicted.
§Patient reported AECOPD in previous year.
¶AECOPD in previous year requiring admission or ED attendance.
**Elective or emergency admission.
††Uses age-adjusted Charlson Comorbidity Index.
‡‡Measured by the clinical COPD questionnaire.
§§30-day death or readmission.
AECOPD, acute exacerbation of COPD; AUROC, area under the receiver operating characteristic; BMI, body mass index; ED, emergency department; mMRC, modified Medical Research Council; n/a, not available.