Table 4

The presence and extent of chest CT abnormalities in children born very preterm

PretermPreterm without BPD (n=50)Preterm with BPD (n=83)Hodges-Lehman median difference (95% CI)
Structural abnormalities on chest CT
 Presence, n participants (%)123 (92)44 (88)79 (95)
 Extent (total CT score)5 (3–9)4 (1–7)6 (4–11)2 (1 to 4); p=0.008*
Linear/triangular subpleural opacities
 Presence112 (84%)39 (78%)73 (88%)
 Extent3 (1–5)2 (1–3)3 (2–6)2 (1 to 2); p<0.001*
Decreased pulmonary attenuation—inspiration
 Presence40 (30%)9 (18%)31 (37%)*
 Extent0 (0–1)0 (0–0)0 (0–1)0 (0 to 0); p=0.013*
Decreased pulmonary attenuation—expiration
 Presence58 (44%)23 (46%)35 (42%)
 Extent0 (0–2)0 (0–2)0 (0–2)0 (0 to 0); p=0.926
Decreased bronchial: arterial ratio
 Presence2 (2%)1 (2%)1 (1%)
 Extent0 (0–0)0 (0–0)0 (0–0)0 (0 to 0); p=0.708
Bronchiectasis
 Presence12 (9%)4 (8%)8 (10%)
 Extent0 (0–0)0 (0–0)0 (0–0)0 (0 to 0); p=0.801
Bronchial wall thickening
 Presence58 (44%)20 (40%)38 (46%)
 Extent0 (0–3)0 (0–2)0 (0–3)0 (0 to 0); p=0.473
Bullae
 Presence2 (2%)0 (0%)2 (2%)
 Extent0 (0–0)0 (0–0)0 (0–0)0 (0 to 0); p=0.271
Emphysema
 Presence4 (3%)0 (0%)4 (5%)
 Extent0 (0–0)0 (0–0)0 (0–0)0 (0 to 0); p=0.116
Collapse/consolidation
 Presence15 (11%)1 (2%)14 (17%)*
 Extent0 (0–0)0 (0–0)0 (0–0)0 (0 to 0); p=0.008*
  • Presence indicates the number (%) of preterm children with the particular structural abnormality described. Extent scores were derived as described by Aukland et al,21 where each parameter has a maximum score of 6 (according to the number of affected lobes) except for collapse/consolidation (maximum=2) leading to a possible total CT score of 50. Extent scores are expressed as median (IQR). Difference in presence of abnormality between groups assessed using theχ2 test and difference in extent assessed using the Mann-Whitney U test.

  • *Represents significant difference between the preterm groups with and without BPD (p<0.05).

  • BPD, bronchopulmonary dysplasia.