Table 4

Multivariate models in sample with anatomic, Pcrit and activated EMGgg measures

VariableOR (95% CI)*p Value†
Model 0: Covariates only
N OSAS=32, N Controls=23, AUC=0.680
 Age1.33 (0.71 to 2.50)0.368
 Male2.72 (0.81 to 9.07)0.105
 African American0.85 (0.20 to 3.63)0.822
 BMI Z-score1.34 (0.77 to 2.33)0.301
Model 1: Anatomy adjusted for covariates
N OSAS=32, N Controls=23, AUC=0.844
 ATV 4.57 (1.53 to 13.6) 0.006
 NPAV 0.45 (0.20 to 1.02)0.054
Model 2: Pcrit adjusted for covariates
N OSAS=32, N Controls=23, AUC=0.841
 Activated Pcrit2.04 (0.93 to 4.47)0.077
 Hypotonic Pcrit 2.26 (1.04 to 4.90) 0.039
Model 3: Activated EMG adjusted for covariates
N OSAS=32, N Controls=23, AUC=0.747
 EMGgg slope (activated) 6.74 (1.05 to 43.1) 0.044
Model 4: Anatomy+Pcrit+activated EMGgg adjusted for covariates
N OSAS=32, N Controls=23, AUC=0.958
 ATV 9.05 (1.56 to 52.5) 0.014
 NPAV 0.04 (0.004 to 0.45) 0.009
 Activated Pcrit 7.72 (1.40 to 42.6) 0.190
 Hypotonic Pcrit1.92 (0.66 to 5.60)0.231
 EMGgg slope (activated) 33.8 (1.17 to 980.7) 0.040
Final model: significant variables adjusted for covariates
N OSAS=32, N Controls=23, AUC=0.951
 ATV 10.0 (1.78 to 56.4) 0.009
 NPAV 0.05 (0.01 to 0.43) 0.007
 Activated Pcrit 8.79 (1.70 to 45.6) 0.010
 EMGgg slope (activated) 24.0 (1.10 to 521.1) 0.043
  • *OR associated with a 1 SD increase in continuous variables or between groups for categorical variables.

  • †p Value from logistic regression model.

  • ‡Model includes listed predictors and covariates shown in Model 0. Significant estimates (p<0.05) are shown in bold.

  • ATV, adenotonsillar volume; AUC, area under the receiver operating characteristic curve; BMI, body mass index; EMGgg, genioglossal electromyogram; NPAV, nasopharyngeal airway volume; OSAS, obstructive sleep apnoea syndrome; Pcrit, critical closing pressure.