Table 5

Associations with evaluated contacts (of index cases with TB at any site) with active TB

Characteristics of the index caseContact diagnosed with active TB
Yes (row %)*No*aOR (95%CI)p Value
Total263 (1.8%)14 351N/aN/a
UK born
 Yes71 (2.3%)29731.31 (0.86 to 1.99)0.41
 No, long-term migrant159 (1.6%)98341
 No, recent migrant33 (2.1%)15441.23 (0.71 to 2.15)
History of drug use
 Yes18 (2.9%)6121.06 (0.56 to 2.01)0.85
 No245 (1.8%)13 7391
History of homelessness
 Yes13 (2.6%)4850.77 (0.36 to 1.66)0.51
 No250 (1.8%)13 8661
Former prisoner
 Yes9 (2.8%)3121.02 (0.37 to 2.84)0.96
 No254 (1.8%)14 0391
Sex
 Male164 (2.0%)78841.35 (0.95 to 1.91)0.09
 Female99 (1.5%)64671
Ethnicity
 Indian39 (1.2%)31301<0.01
 Black African103 (3.0%)33241.95 (1.17 to 3.26)
 White32 (1.7%)19100.81 (0.44 to 1.50)
 Other89 (1.5%)59871.03 (0.63 to 1.67)
Culture
 Positive225 (2.4%)931610.12
 Negative71 (0.8%)40330.70 (0.43 to 1.15)
 Not done7 (0.7%)10020.50 (0.23 to 1.09)
Disease type
 Non-pulmonary and non-laryngeal41 (0.6%)63911<0.01
 Pulmonary smear-negative44 (1.4%)31072.10 (1.20 to 3.69)
 Pulmonary smear-positive166 (4.3%)36966.71 (4.11 to 11.0)
 Pulmonary, smear unknown or laryngeal12 (1.0%)11571.39 (0.73 to 2.64)
BCG
 Not vaccinated51 (1.6%)32220.78 (0.51 to 1.18)0.28
 Vaccinated177 (2.0%)85021
 Unknown35 (1.3%)26270.73 (0.44 to 1.19)
Clinic case count* (linear, 100 cases/year) Embedded Image s=0.520.97 (0.68 to 1.40)0.89
Age of index case
 0–14 years25 (5.7%)4171<0.01
 15 years and over238 (1.7%)13 9340.25 (0.13 to 0.48)
Notification rate*† (linear, 10 cases/100 000 population/year) Embedded Image s=1.91.05 (0.95 to 1.17)0.32
Age of contact
 15 years and over151 (1.5%)10 1330.55 (0.40 to 0.75)<0.01
 0–14 years112 (2.6%)42181
Contact screened at clinic
 Yes233 (1.9%)12 1621.38 (0.81 to 2.37)0.24
 No30 (1.4%)21891
  • *Mean and SD presented for continuous variables.

  • †Notification rate in the year and local authority in which the index case was notified. N=14 614.

  • aOR, adjusted OR.