Table 1

Basic demographics of TB cases in HCWs and non-HCWs

	HCW TB cases (n=2320)		Non-HCW TB cases (n=27 681)		Chi squared p Value
	n	Per cent	n	Per cent	Chi squared p Value
Sex	n=2295		n=27 643
Male	714	31.1	16 488	59.6	<0.001
Age group (years)	n=2320		n=27 681
16–24	126	5.5	5213	18.8	<0.001
25–34	785	33.8	9273	33.5
35–44	843	36.4	5976	21.6
45–54	400	17.2	4161	15.0
55–64	166	7.1	3057	11.0
UK-born	n=2227		n=27 075
Yes	334	15.0	6138	22.7	<0.001
Country of birth	n=2182		27 681
UK	334	15.3	6138	23.0	<0.001
India	559	25.6	5913	22.2
Pakistan	128	5.9	3860	14.5
Somalia	31	1.4	1535	5.8
Nigeria	106	4.9	660	2.5
Nepal	74	3.4	654	2.4
Zimbabwe	200	9.2	459	1.7
Philippines	249	11.4	322	1.2
Kenya	44	2.0	331	1.2
South Africa	63	3.0	159	0.6
All other countries	394	18.1	6627	24.9
Ethnicity	n=2252		n=27 201
White	270	12.0	4824	17.7	<0.001
Black African	644	28.6	4936	18.0
Black Caribbean	45	2.0	555	2.0
Black other	18	0.8	247	0.9
Indian	670	26.6	7201	26.5
Pakistani	171	7.6	4810	17.7
Bangladeshi	24	1.1	1169	4.3
Chinese	23	1.0	378	1.4
Mixed/other	387	17.2	3081	11.3
Years since entry to the UK	n=1633		n=18 906
<2	161	9.8	4188	22.2	<0.001
2–5	473	29.0	5825	30.8
6–10	624	38.4	3840	20.3
>10	375	22.9	5053	26.7
Site of disease	n=2312		n=27 611
Pulmonary	1005	43.5	14 423	52.2	<0.001
Extrapulmonary only	1307	56.5	13 188	47.8
Social risk factor	n=1852		n=22 221
Yes	43	2.3	2754	12.4	<0.001
Previous diagnosis	n=2219		n=26 502
Yes	97	4.4	1687	6.4	<0.001
BCG vaccination*	n=1665		n=19 356
Yes	1456	87.5	14 282	73.8	<0.001
Time to treatment start (pulmonary cases)	n=765		n=10 631
<2 months after symptom onset	337	44.0	4885	45.9	0.162
2–4 months after symptom onset	214	28.0	3101	29.2
>4 months after symptom onset	214	28.0	2645	24.9
Clustered (≥2 indistinguishable 24 loci MIRU-VNTR)	n=883		n=11 554
Yes	423	48.0	6402	55.4	<0.001
MDR-TB	n=1425		n=17 226
Yes	20	1.4	285	1.7	0.473

*At any time. HCWs, healthcare workers; MIRU-VNTR, mycobacterial interspersed repetitive unit-variable number tandem; MDR-TB, multidrug-resistant TB.