Descriptive characteristics of cohorts included in discovery and follow-up (age and lung function measurements as at first time point)
| Study | No. of participants | Women, % | Ever-smokers, % | Mean age, years (SD) | Age range, years | Mean FEV1, L (SD) | Mean FVC, L (SD) | Mean FEV1/FVC (SD) | Mean annual change in FEV1, mL (SD) | Range of annual change in FEV1, mL |
|---|---|---|---|---|---|---|---|---|---|---|
| BHS | 4167 | 56.1 | 48.8 | 38.6 (10.6) | 25–82 | 3.35 (0.87) | 4.26 (1.04) | 0.79 (0.08) | −27.2 (20.3) | −150 to 90 |
| CCHS | 9016 | 55.6 | 75.7 | 46.4 (11.1) | 25–85 | 2.98 (0.91) | 3.69 (1.08) | 0.81 (0.09) | −30.1 (29.7) | −260 to 220 |
| LHS | 3502 | 36.6 | 100 | 48.6 (6.7) | 35–62 | 2.77 (0.63) | 4.3 (0.94) | 0.65 (0.07) | −51.0 (55.6) | −338 to 168 |
BHS, Busselton Health Study; CCHS, Copenhagen City Heart Study; LHS, Lung Health Study.