Associations of cholesterol and lipoproteins with high attenuation area (HAA)
| % change in HAA (95% CI)* | p Value | |
|---|---|---|
| Total cholesterol | −1.32 (−1.89 to −0.75) | <0.001 |
| HDL-C, mg/dL | −2.12 (−2.79 to −1.44) | <0.001 |
| LDL-C, mg/dL | −0.84 (−1.41 to −0.28) | 0.004 |
| Triglycerides | −0.82 (−1.45 to −0.18) | 0.01 |
| Large HDL, 9.4–14 nm | −1.10 (−1.93 to −0.26) | 0.01 |
| Medium HDL, 8.2–9.4 nm | −2.56 (−3.31 to −1.80) | <0.001 |
| Small HDL, 7.3–8.2 nm | −2.69 (−3.44 to −1.94) | <0.001 |
| Large LDL, 20.5–23 nm | −1.36 (−2.06 to −0.66) | <0.001 |
| Small LDL, 18–20.5 nm | −0.73 (−1.56 to 0.11) | 0.09 |
| Apolipoprotein A-1 | −1.66 (−2.36 to −0.97) | <0.001 |
| Apolipoprotein B | −0.69 (−1.37 to −0.01) | 0.048 |
Solid lines separate distinct models. Each model includes all exposure variables listed and is additionally adjusted for age, gender, race/ethnicity, educational attainment, height, body mass index, waist circumference, smoking status, cigarette pack-years, glomerular filtration rate, diuretic use, statin use, presence of hypertension, presence of diabetes mellitus, coronary artery calcium, study site, milliampere dose, total volume imaged lung, per cent emphysema on CT, interleukin-6 and C reactive protein.
*Reported per SD in each exposure variable.