Table 2

Spirometric data before and after inhaled bronchodilator in healthy children and those with asthma measured on the first visit

Healthy children (n=364)*Children with asthma (n=244)*
SpirometryBaseline (mean ±SD)Post-bronchodilator (mean±SD)p ValueBaseline (mean ±SD)Post-bronchodilator (mean ±SD)p Value
FVC (L)1.17±0.161.21±0.060.7201.16±0.201.24±0.11†0.041
FEV1 (L)1.11±0.121.16±0.070.5671.01±0.151.11±0.09†0.032
FEV0.75 (L)1.01±0.101.06±0.050.4820.91±0.121.03±0.10†0.022
FEV0.5 (L)0.90±0.090.94±0.050.5380.81±0.110.92±0.10†0.028
FEF25–75 (L/s)1.50±0.311.65±0.280.5681.16±0.381.54±0.41†0.018
FEF25 (L/s)0.99±0.201.09±0.190.5640.77±0.251.03±0.31†0.024
FEF50 (L/s)1.93±0.262.11±0.380.5351.4±0.482.01±0.56†0.019
FEF75 (L/s)1.26±0.141.38±0.250.5080.99±0.321.34±0.37†0.025
PEF (L/s)2.47±0.272.69±0.440.5012.22±0.592.64±0.84†0.042
  • Data, as absolute values, are shown as group mean and SD.

  • *Number of children with successful spirometry on the first visit.

  • †Statistically significant increase following bronchodilator (p<0.05).

  • FEF, forced expiratory flow; PEF, peak expiratory flow.