Adjusted OR and HR for the association between bronchiectasis and coronary heart disease (CHD) or stroke from sensitivity analyses
| Sensitivity analysis performed | OR for CHD (95% CI) | OR for stroke (95% CI) | HR for CHD (95% CI) | HR for stroke (95% CI) |
|---|---|---|---|---|
| Excluding individuals with coexisting diagnosis of COPD (n=7099)* | 1.19 (1.09 to 1.29) | 1.91 (1.81 to 2.02) | 1.36 (1.15 to 1.60) | 1.77 (1.55 to 2.02) |
| Only including individuals without comorbidities associated with the aetiology of bronchiectasis (n=4027)* | 1.21 (1.08 to 1.34) | 1.93 (1.80 to 2.07) | 1.28 (1.08 to 1.48) | 1.84 (1.55 to 2.17) |
| Only including current smokers (n=1 401 175)* | 1.29(1.13 to 1.47) | 1.79 (1.66 to 1.95) | 1.41 (1.10 to 1.79) | 1.65 (1.37 to 1.99) |
| Only including never-smokers (n=1 644 170)* | 1.36 (1.23 to 1.50) | 1.98 (1.85 to 2.13) | 1.47 (1.19 to 1.80) | 1.80 (1.51 to 2.14) |
| Excluding individuals with missing smoking information (n=3 698 015)* | 1.35 (1.27 to 1.44) | 1.91 (1.84 to 2.00) | 1.44 (1.27 to 1.63) | 1.71 (1.54 to 1.90) |
| Competing risk adjustment | n/a | n/a | 1.39 (1.22 to 1.59) | 1.76 (1.54 to 2.01) |
*Adjusted for age, sex, smoking, diabetes mellitus, hypertension, hyperlipidaemia and family history of cardiovascular disease.