Table 4

Histology of screening-detected lung cancers of all rounds

Round 1p Value*Round 2p Value†Round 3p Value‡Round 4
nPer centnPer centnPer centnPer cent
0.010.0010.06
Histology
 Adenocarcinoma3547.33560.33748.12350.0
 Squamous cell carcinoma1520.335.21620.81021.7
 BAC22.735.267.848.7
 SCLC11.423.456.536.5
 NSCLC, not specified22.748.7
 Others19§25.715¶25.913**16.92††4.3
Total74100581007710046100
  • *p Value: difference in histology between the first and last screening rounds. Fisher's exact test was used.

  • †p Value: difference in histology between the second and last screening rounds. Fisher's exact test was used.

  • ‡p Value: difference in histology between the third and last screening rounds. Fisher's exact test was used.

  • §Others in round 1: 5 large cell carcinomas, 1 mixed NSCLC/SCLC, 4 carcinoids, 1 other, 3 no diagnosis was possible, 2 adenosquamous and 3 large-cell neuroendocrine carcinoma.

  • ¶Others in round 2: 10 large-cell carcinomas, 2 adenosquamous cell carcinoma and 3 cancers without a diagnosis were included in the group of others; in round 4: 2 cancers without a possible diagnosis were included in the group of others.

  • **Others in round 3: 2 large-cell carcinomas, 1 mixed NSCLC/SCLC, 2 carcinoids, 1 large-cell neuroendocrine carcinoma and 7 without a diagnosis; in round 4: 2 cancers without a diagnosis.

  • ††Others in round 4: 2 with no diagnosis possible. No other types of lung cancers were detected in this round.

  • BAC: bronchoalveolar carcinoma; NSCLC, non-small cell lung carcinoma; SCLC: small-cell carcinoma.