Absolute Change From KIWI Baseline
| Mean (SD) | n | KIWI Part B1,2
(Week 24) | n | KLIMB (Week 84a) |
|---|---|---|---|---|
| Sweat chloride, mmol/L | 25 | −46.9 (26.6) P < 0.0001 | 20 | −54.7 (26.0) P < 0.0001 |
| FE-1, µg/g | 27 | 99.8 (138.4) P = 0.0009 | 17 | 128.8 (170.1) P < 0.01 |
| IRT, ng/mL | 25 | −20.7 (24.0) P = 0.0002 | 21 | −15.9 (25.2) P < 0.05 |
| Weight-for-age z score | 33 | 0.2 (0.3) P < 0.0001 | 28 | 0.2 (0.6) P = 0.1 |
| BMI-for-age z score | 32 | 0.4 (0.4) P < 0.0001 | 28 | 0.3 (0.6) P < 0.05 |
| Stature-for-age z score | 32 | −0.01 (0.3) P = 0.84 | 28 | 0.1 (0.4) P = 0.18 |
aPatients treated for a total of 108 weeks.