Pneumolysin-mediated formation of neutrophil: platelet aggregates
| System | Neutrophil:platelet aggregates (mean fluorescence intensity ± SDs) |
|---|---|
| Background | 11.24 ± 5.0 |
| ADP (100 μM) | 20.63 ± 5.6* |
| Ply (10 ng/ml) | 18.90 ± 10.7* |
| Ply (20 ng/ml) | 27.92 ± 16.08* |
| Ply (40 ng/ml) | 33.21 ± 17.09* |
| Ply (80 ng/ml) | 42.09 ± 23.05* |
| Delta6Ply (80 ng/ml) | 14.86 ± 7.49 |
*p <0.05 – p <0.0009