Interaction between early-onset asthma and smoking on post-BD FEV1/FVC (% predicted)
| Smoking (≥1 pack-year) | Post-BD FEV1/FVC | p[Interaction] | |
|---|---|---|---|
| Control (never asthma) | No | Reference | |
| Yes | −1.96 (−3.36 to −0.57)* | ||
| Early-onset | No | −5.16 (−6.97 to −3.35)† | 0.34 |
| Yes | −8.83 (−11.78 to −5.89)† |
Adjusted for smoking status, social class, family history of obstructive lung disease, childhood lung infection.
*p<0.01; †p<0.001.
BD, bronchodilator.