Table 4

Cardiopulmonary exercise test (CPET) cardiovascular responses at peak exercise comparing extremely preterm and control children

Mod/sev BPD (mean±SD)No/mild BPD (mean±SD)Control (mean±SD)
Exercise time (min:sec)6:52±2:018:33±2:127:45±1:39
Heart rate (beats/min)175.8±14.9178.1±19.1182.5±15.5
Work (W)89.2±32.4104.5±33.2109.6±35.8
VO2peak (L/min)1.65±0.651.83±0.551.87±0.43
VO2peak % predicted (%)†89.3±23.0107.4±22.7103.4±26.5
VO2peak relative (mL/kg/min)†36.9±10.744.6±9.242.6±9.6
VCO2peak (L/min)*1.71±0.621.98±0.652.03±0.49
  • Post hoc ANOVA one-way comparisons (mean±SE).

  • VO2peak relative: mod/sev BPD 5.73±1.94 L/min<control*; mod/sev BPD 7.72±2.02 L/min<no/mild BPD†.

  • VO2peak % predicted: mod/sev BPD 14±5%<control*; mod/sev BPD 18±5%<no/mild BPD†.

  • VCO2 peak: No statistically significant one-way differences.

  • *p<0.05; †p<0.01.

  • ANOVA, analysis of variance; BPD, bronchopulmonary dysplasia; mod/sev, moderate/severe; RQ, respiratory quotient; VCO2peak, peak carbon dioxide uptake; VO2, oxygen uptake.