Summary of findings; intervention: physical rehabilitation
| WHO domain outcome | Review author; N studies: N patients | Pooled effect (95% CI) | GRADE of evidence | Explanation |
|---|---|---|---|---|
| Activity limitation | ||||
| Functional exercise capacity | Connolly et al13 6 483* | Unable to pool data due to variability in use of outcome measures across individual studies | ϴ Very low | Downgraded −3 due to variability in multiple aspects of methodology across studies, risk of bias and differences in data reporting |
| Participation restriction | ||||
| Health-related quality of Life | Connolly et al13 2 254* | Unable to pool data due to variability in use of outcome measures across individual studies and small study number | ϴ Very low | Downgraded −3 due to variability in multiple aspects of methodology across studies, risk of bias and differences in data reporting |
| Healthcare utilisation | ||||
| Mortality | Connolly et al13 6 483 | Unable to pool data due to variation in study design; no deaths reported in two studies; no difference in mortality rates between intervention and control groups in remaining four studies | ϴϴ Low | Downgraded −2 due to serious inconsistency and imprecision |
| Adverse events | ||||
| Non-mortality adverse events | Connolly et al13 4 376 | Three studies reported no adverse events; one study reported no significant difference between groups for adverse events (n=1 event only) | ϴϴ Low | Downgraded −2 due to lack of reported data from two studies and serious imprecision |
Comparison: usual care. Stage of recovery: post-ICU discharge. *Data reported are overall number of participants enrolled in each study. Multiple outcome measures were observed across studies with variable numbers of patients for each measure according to each study.
ICU, intensive care unit.