Table 2

Associations (coefficient and 95% CI) between birth weight and FEV1 (mL) and FVC (mL) at every age in all persons

FEV1 (mL)
Birth weight (per 1 kg increase)Age 43 years (N=2836)Age 53 years (N=2392)Age 60–64 years (N=1788)
M0: unadjusted247.3198.7 to 295.8214.9163.2 to 266.7201.7139.6 to 263.8
M1: M0+sex131.994.5 to 169.391.952.9 to 130.8106.860.3 to 153.2
M2:M1+adult height*39.33.8 to 74.9−2.6−39.1 to 34.06.8−38.0 to 51.7
M3: M2+adult covariates†25.7−13.5 to 64.817.7−21.9 to 57.322.3−29.0 to 73.7
M4: M3+early life covariates‡42.4−2.3 to 87.031.6−13.3 to 76.539.4−18.1 to 96.8
FVC (mL)
Birth weight (per 1 kg increase)Age 43 years (N=2774)Age 53 years (N=2235)Age 60–64 years (N=1688)
M0: unadjusted330.8266.5 to 395.0297.3227.7 to 366.9239.8159.7 to 319.8
M1: M0+sex188.4137.1 to 239.6154.4104.0 to 204.8112.354.2 to 170.4
M2: M1+adult height*59.711.3 to 108.126.1−19.6 to 71.8−31.2−85.2 to 22.8
M3: M2+adult covariates†34.4−20.0 to 88.837.3−15.0 to 89.6−20.4−84.5 to 43.7
M4: M3+early life covariates‡43.1−18.6 to 104.760.72.1 to 119.3−13.2−85.7 to 59.3
  • Bold indicates where significance level is P<0.05.

  • *Adjusted for age at 2006–2010 follow-up (age 60–64 years).

  • †Adult covariates included education level, smoking status, asthma status, smoking pack years.

  • ‡Early life covariates included weight gain at age 2 years, lower respiratory tract infections under age 2 years and childhood social class at age 4 years.