Table 5

Associations (coefficient and 95% CI) between weight gain up to age 2 years and FEV1 (mL) and FVC (mL) at age 43 years, 53 years and 60–64 years in men and women: fully adjusted model*

All personsFEV1 (mL)
Age 43 years (N=2836)Age 53 years (N=2392)Age 60–64 years (N=1788)
Weight gain up to 2 years of age (per 1 kg increase)17.1(0.7 to 33.5)4.8(−11.7 to 21.3)10.8(−9.0 to 30.6)
 FVC (mL)
Age 43 years (N=2774)Age 53 years (N=2235)Age 60–64 years (N=1688)
Weight gain up to 2 years of age (per 1 kg increase)10.6(−11.8 to 33.1)13.0(−8.0 to 34.0)1.4(−23.9 to 26.7)
FEV1 (mL)
MenAge 43 years (N=1385)Age 53 years (N=1174)Age 60–64 years (N=856)
Weight gain up to 2 years of age (per 1 kg increase)20.3(−7.2 to 47.7)−3.6(−30.0 to 22.9)30.9(−2.7 to 64.6)
FVC (mL)
Age 43 years (N=1326)Age 53 years (N=1060)Age 60–64 years (N=777)
Weight gain up to 2 years of age (per 1 kg increase)2.5(−35.4 to 40.4)24.5(−9.8 to 58.8)34.7(−11.8 to 81.3)
FEV1 (mL)
WomenAge 43 years (N=1451)Age 53 years (N=1218)Age 60–64 years (N=932)
Weight gain up to 2 years of age (per 1 kg increase)15.6(−3.1 to 34.3)13.4(−6.4 to 33.1)−1.0(−23.2 to 21.2)
FVC (mL)
Age 43 years (N=1448)Age 53 years (N=1175)Age 60–64 years (N=911)
Weight gain up to 2 years of age (per 1 kg increase)23.6(−1.5 to 48.8)5.8(−19.0 to 30.6)−15.5(−41.9 to 10.9)
  • Bold indicates where significance level is P<0.05.

  • *Fully adjusted model: height, adult covariates included education level, smoking status, asthma status, smoking pack years; early life covariates included birth weight, lower respiratory tract infections under age 2 years and childhood social class at age 4 years; adjusted additionally for age at 2006–2010 follow-up (aged 60–64 years).