Table 3

Treatment received and mortality rates across the total sample according to the different drug resistance patterns (n=689)

MDRMDR+FQresMDR+INJresXDRTotal
DeathsRate95% CIDeathsRate95% CIDeathsRate95% CIDeathsRate95% CIDeathsRate95% CI
Type 1: regimen does not include INJ or FQ1968.3543.59107.15n.d.164.109.03455.07322.997.4171.282558.5639.5786.67
 Only FLDs1763.2039.29101.66n.d.164.109.03455.071966.2542.26103.86
 Only PT/ETH and/or PAS and/or CS2222.2255.58888.54322.997.4171.28642.8319.2495.33
Type 2: regimen includes INJ417.036.3945.3717.451.0552.86130.304.27215.1216.480.9146.01712.586.0026.38
 INJ only00.00n.d.n.d.00.00
 INJ+(PT/ETH or PAS or CS)418.266.8548.6417.451.0552.861188.6826.581339.4516.480.9146.01713.656.5128.62
 INJ+(PT/ETH or PAS or CS)+AMOX00.00n.d.00.00
Type 3: regimen includes FQ159.145.5115.16517.377.2341.74118.944.9516.141516.8210.1427.905011.178.4614.73
 FQ only11250.00176.088873.84113.991.9799.29227.666.92110.61
 FQ+(PT/ETH or PAS or CS)148.875.2514.97214.143.5456.5598.524.4316.371216.699.4829.384110.457.7014.20
 FQ+(PT/ETH or PAS or CS)+AMOX00.00n.d.226.706.68106.77211.472.8745.88317.375.6053.86714.476.9030.36
Type 4: regimen includes INJ and FQ557.525.779.8088.414.2116.82139.446.7113.29138.024.6613.821118.096.729.75
 INJ+FQ only00.00n.d.00.00
 INJ+FQ+(PT/ETH or PAS or CS)507.495.689.8967.243.2516.122211.037.2616.7598.604.4816.53898.206.6610.09
 INJ+FQ+(PT/ETH or PAS or CS)+AMOX58.293.4519.93216.344.0965.33117.344.0613.2546.972.6218.58227.865.1811.94
  • AMOX, amoxicillin/clavulanate; CS, cycloserine; FLDs, first-line drugs; FQ, fluoroquinolones; INJ, second-line injectable agents; MDR, multidrug-resistance, no additional resistance to FQs or second-line injectable agents; PAS, p-aminosalicylic acid; PT/ETH, prothionamide/ethionamide; XDR, extensive drug resistance.