Table 4

Effect of CPAP treatments on BP levels in the per-protocol population

BP, mm HgFP-CPAP (n=133)AutoCPAP (n=143)Intergroup rawIntergroup adjusted*
BaselineFollow-upp ValueBaselineFollow-upp ValueDifferences (95% CI)p ValueDifferences (95% CI)p Value
Office SBP136.0±15.4132.9±14.20.007134.6±17.1133.9±16.70.52−2.4 (−5.5 to 0.7)0.13−1.8 (−4.6 to 1.0)0.20
Office DBP79.5±9.676.1±9.3<0.00180.5±9.778.0±8.90.001−1.0 (−3.0 to 1.0)0.35−1.4 (−3.2 to 0.3)0.11
24 h SBP129.0±12.6126.8±11.40.012127.8±13.5127.6±12.90.82−2.0 (−4.4 to 0.3)0.09−1.7 (−3.9 to 0.5)0.13
24 h DBP78.8±8.276.7±7.5<0.00178.6±8.277.8±7.50.08−1.3 (−2.6 to −0.03)0.046−1.3 (−2.4 to −0.1)0.032
24 h mean BP95.4±8.293.4±7.5<0.00194.8±8.894.1±7.90.24−1.4 (−2.9 to 0.2)0.08−1.2 (−2.5 to 0.2)0.09
Daytime SBP134.4±13.8131.8±11.90.001132.5±13.6132.5±12.90.94−2.5 (−5.2 to 0.2)0.07−1.8 (−4.2 to 0.5)0.13
Daytime DBP82.8±9.080.3±8.3<0.00182.5±8.581.3±8.10.031−1.4 (−2.8 to 0.1)0.07−1.3 (−2.6 to 0.1)0.07
Daytime mean BP99.6±9.297.0±8.2<0.00198.6±8.997.9±8.20.28−1.9 (−3.6 to −0.1)0.041−1.6 (−3.1 to −0.01)0.049
Nighttime SBP119.3±12.6117.7±12.60.12119.3±15.3118.8±14.30.58−1.0 (−3.6 to 1.6)0.45−1.0 (−3.4 to 1.4)0.40
Nighttime DBP71.4±7.970.3±7.40.04071.5±9.071.3±7.80.81−1.0 (−2.6 to 0.5)0.19−1.0 (−2.4 to 0.3)0.13
Nighttime mean BP87.6±8.186.6±8.00.1287.8±10.187.4±8.90.49−0.6 (−2.3 to 1.2)0.52−0.6 (−2.2 to 0.9)0.43
  • Data are presented as mean±SD.

  • *Adjusted by baseline BP values.

  • AutoCPAP, auto-adjusted CPAP; BP, blood pressure; DBP, diastolic blood pressure; FP-CPAP, fixed-pressure CPAP; SBP, systolic blood pressure.