Emphysema on CT | ||
---|---|---|
Absent | Present | |
Number of participants | 6233 | 538 |
Age, years | 62.1 (10.3) | 63.1 (10.0) |
Males | 2902 (47%) | 290 (54%) |
Race | ||
White | 2365 (38%) | 241 (45%) |
African–American | 1703 (27%) | 169 (31%) |
Hispanic/Latino | 1407 (23%) | 83 (15%) |
Asian | 758 (12%) | 45 (8%) |
Smoking status | ||
Never | 2915 (47%) | 157 (29%) |
Former | 2459 (39%) | 287 (53%) |
Current | 859 (14%) | 94 (17%) |
Pack-years | 14 (3, 32) | 19 (6, 42) |
Body mass index, kg/m2 | 28.2 (5.3) | 29.9 (7.3) |
Education | ||
Less than high school | 1147 (18%) | 75 (14%) |
High school | 1139 (18%) | 95 (18%) |
Some college but no degree | 1003 (16%) | 102 (19%) |
Associate/technical degree | 770 (12%) | 53 (10%) |
Bachelor's degree | 1062 (17%) | 107 (20%) |
Graduate degree | 1112 (18%) | 106 (20%) |
Site | ||
Forsyth County, North Carolina | 994 (16%) | 75 (14%) |
Upper Manhattan and the Bronx, New York | 1014 (16%) | 86 (16%) |
Baltimore County, Maryland | 929 (15%) | 133 (25%) |
Minneapolis, Minnesota | 963 (15%) | 99 (18%) |
Chicago, Illinois | 1074 (17%) | 88 (16%) |
Los Angeles County, California | 1259 (20%) | 57 (11%) |
Physician diagnosis of emphysema | 69 (1%) | 34 (6%) |
Physician diagnosis of asthma | 561 (9%) | 99 (18%) |
Prebronchodilator airflow measures | ||
FEV1, L | 2.38 (0.72) | 2.38 (0.86) |
FEV1/FVC | 0.76 (0.08) | 0.68 (0.13) |
Restrictive ventilatory defect | 309 (9%) | 12 (4%) |
Agatston score | 0 (0, 82) | 11 (0, 149) |
Per cent emphysema | 2.6 (1.1, 4.8) | 12.2 (8.9, 15.7) |
Emphysema on CT defined as per cent emphysema greater than the upper limit of normal according to reference equations. Data are n, n/N (%), mean (SD) or median (IQR). Percentages may not sum to 100% due to rounding.
Airflow obstruction defined as FEV1/FVC <0.7. Pack-years enumerated among ever-smokers only. Prebronchodilator airflow measures are calculated only among the 3830 participants who underwent spirometry in 2004–2006. For 13 participants with current smoking, reference equations for the upper limit of normal could not be calculated due to missing smoking intensity data; nonetheless, these participants were included in analyses using the exposure of continuous per cent emphysema.