Table 1

Baseline characteristics of participants in the Multi-Ethnic Study of Atherosclerosis, by presence of emphysema on CT, 2000–2002

Emphysema on CT
AbsentPresent
Number of participants6233538
Age, years62.1 (10.3)63.1 (10.0)
Males2902 (47%)290 (54%)
Race
 White2365 (38%)241 (45%)
 African–American1703 (27%)169 (31%)
 Hispanic/Latino1407 (23%)83 (15%)
 Asian758 (12%)45 (8%)
Smoking status
 Never2915 (47%)157 (29%)
 Former2459 (39%)287 (53%)
 Current859 (14%)94 (17%)
Pack-years14 (3, 32)19 (6, 42)
Body mass index, kg/m228.2 (5.3)29.9 (7.3)
Education
 Less than high school1147 (18%)75 (14%)
 High school1139 (18%)95 (18%)
 Some college but no degree1003 (16%)102 (19%)
 Associate/technical degree770 (12%)53 (10%)
 Bachelor's degree1062 (17%)107 (20%)
 Graduate degree1112 (18%)106 (20%)
Site
 Forsyth County, North Carolina994 (16%)75 (14%)
 Upper Manhattan and the Bronx, New York1014 (16%)86 (16%)
 Baltimore County, Maryland929 (15%)133 (25%)
 Minneapolis, Minnesota963 (15%)99 (18%)
 Chicago, Illinois1074 (17%)88 (16%)
 Los Angeles County, California1259 (20%)57 (11%)
Physician diagnosis of emphysema69 (1%)34 (6%)
Physician diagnosis of asthma561 (9%)99 (18%)
Prebronchodilator airflow measures
 FEV1, L2.38 (0.72)2.38 (0.86)
 FEV1/FVC0.76 (0.08)0.68 (0.13)
 Restrictive ventilatory defect309 (9%)12 (4%)
Agatston score0 (0, 82)11 (0, 149)
Per cent emphysema2.6 (1.1, 4.8)12.2 (8.9, 15.7)
  • Emphysema on CT defined as per cent emphysema greater than the upper limit of normal according to reference equations. Data are n, n/N (%), mean (SD) or median (IQR). Percentages may not sum to 100% due to rounding.

  • Airflow obstruction defined as FEV1/FVC <0.7. Pack-years enumerated among ever-smokers only. Prebronchodilator airflow measures are calculated only among the 3830 participants who underwent spirometry in 2004–2006. For 13 participants with current smoking, reference equations for the upper limit of normal could not be calculated due to missing smoking intensity data; nonetheless, these participants were included in analyses using the exposure of continuous per cent emphysema.