Table 2

Unadjusted and adjusted effect measures for the association between statin use and the risk of active TB

Status of statin useStatin usage rates for all the TB casesStatin usage rates for all the controlsEffect estimates matched by age group, gender and year, RR (95% CI)Confounder-adjusted effect estimates**, RR (95% CI)DRS, adjusted RR (95% CI)
Current use134/8098=0.01617 836/809 800=0.0220.76 (0.64 to 0.90)**0.67 (0.56 to 0.80)***0.64 (0.54 to 0.76)***
Recent use52/8098=0.0065812/809 800=0.0070.87 (0.69 to 1.09)0.87 (0.66 to 1.15)0.78 (0.59 to 1.03)
Past use148/8098=0.01816 996/809 800=0.0210.86 (0.72 to 1.03)0.76 (0.64 to 0.90)**0.72 (0.61 to 0.85)***
Chronic user160/8098=0.02022 153/809 800=0.0270.74 (0.63 to 0.87)***0.66 (0.56 to 0.78)***0.62 (0.53 to 0.72)***
  • The reference group in the calculation of RR is participants who did not use statins.

  • **p<0.01; ***p<0.001.

  • DRS, Disease Risk Score; RR, incidence rate ratio.