Differences within and between groups for each outcome measure at 2 weeks
| Outcome | Differences within groups | Differences between groups (mixed model analysis) | p Value | |
|---|---|---|---|---|
| Week 2 minus week 0 Mean (SEM) | Difference between groups (95% CI) | |||
| IMT (n=34) | Control (n=36) | |||
| MIP % predicted | 17 (4) | 6 (3) | 11 (2 to 20) | 0.024* |
| Fatigue resistance index/1.00 | 0.03 (0.05) | 0.02 (0.5) | 0.02 (−0.15 to 0.12) | 0.816 |
| QOL: SF-36 | 0.08 (0.02) | 0.04 (0.02) | 0.05 (−0.01 to 0.10) | 0.123 |
| QOL: EQ5D | 14 (4) | 2 (4) | 12 (1 to 23) | 0.034* |
| ACIF/1.00 | 0.25 (0.04) | 0.25 (0.04) | 0.00 (−0.12 to 0.12) | 0.974 |
| Dyspnoea at rest/10 | −0.8 (0.4) | −0.4 (0.4) | −0.4 (−1.5 to 0.7) | 0.483 |
| Dyspnoea during exercise/10 | −0.5 (0.4) | 0.2 (0.4) | −0.7 (−1.8 to 0.4) | 0.223 |
*=p<0.05. **=p<0.01. ***=p<0.001. All analyses are intention-to-treat.
ACIF, acute care index of function; IMT, inspiratory muscle training; MIP, maximum inspiratory pressure; QOL, quality of life (SF-36 or EQ5D tools).