Table 1

Sensitivity, specificity, PPV and NPV for different screening thresholds used across published studies on nNO diagnostics,2 but analysed against our data (n=282)

120 nL/min (%)77 nL/min (%)40 nL/min (%)20 nL/min (%)
Sensitivity100 (88.8 to 100)93.6 (78.6 to 99.2)93.6 (78.6 to 99.2)77.4 (58.9 to 90.4)
Specificity68.9 (61.1 to 73.1)84.1 (78.9 to 88.4)94.4 (90.8 to 96.9)97.6 (94.9 to 99.1)
PPV27.4 (19.5 to 36.6)42 (30.2 to 54.5)67.4 (51.5 to 80.9)80.0 (61.4 to 92.3)
NPV100 (97.8 to 100)99.1 (96.7 to 99.9)99.2 (97.0 to 99.9)97.2 (94.4 to 98.9)
  • 95% CIs in brackets.

  • nNO, nasal nitric oxide; NPV, negative predictive value; PPV, positive predictive value.