Anchor-based and distribution-based estimates of the minimum important difference (MID) of the EQ-5D-5L utility index and EQ-VAS
| Approach | Anchor/method | MID estimate | |
|---|---|---|---|
| Utility index | Distribution | 0.5 SD | 0.109 |
| Mean change | GRCQ | 0.054 | |
| Linear regression | CRQ emotion | 0.063 | |
| Linear regression | CRQ mastery | 0.062 | |
| Linear regression | CRQ total | 0.059 | |
| ROC | CRQ emotion | 0.046 | |
| ROC | CRQ mastery | 0.038 | |
| ROC | CRQ total | 0.037 | |
| EQ-VAS | Distribution | 0.5 SD | 10.1 |
| Mean change | GRCQ | 6.9 | |
| Linear regression | CRQ dyspnoea | 6.5 | |
| Linear regression | CRQ fatigue | 7.2 | |
| Linear regression | CRQ emotion | 8.0 | |
| Linear regression | CRQ mastery | 7.6 | |
| Linear regression | CRQ total | 6.7 | |
| ROC | CRQ dyspnoea | 6.5 | |
| ROC | CRQ fatigue | 6.5 | |
| ROC | CRQ emotion | 6.5 | |
| ROC | CRQ mastery | 6.5 | |
| ROC | CRQ total | 6.5 |
CRQ, chronic respiratory questionnaire; GRCQ, global rating of change questionnaire; ROC, receiver operating characteristic curves.