Tolerance parameters in placebo-treated and sildenafil-treated animals
| Placebo | Sildenafil 10 mg/kg/day | p Value | |
|---|---|---|---|
| WCP | 3.8±1.9 | 0.4±6.9 | 0.3 |
| HRCP | −6.8±18.25 | −6.0±21.2 | 0.9 |
| Mean fetal loss rate (%) | 9.1±5.1 | 8.2±12.7 | 0.7 |
| FBW (g) | 43.2±7.5 | 46.2±7.2 | 0.1 |
Values represent mean±SD.
N=5 does and 30 fetuses: placebo group; N=5 does and 34 fetuses sildenafil group.
FBW, fetal body weight; HRCP, heart rate change percentage; WCP, weight change percentage.