FEV1 decline (mL/year) in PiSZ and PiZZ alpha-1 antitrypsin deficiency
| Variable | PiZZ | PiSZ | p Value |
|---|---|---|---|
| Current smoker | −16.0 (−8.1 to −56.6) | −59.6 (−16.8 to −79.4) | 0.287 |
| Ex smoker | −37.0 (−10.0 to −76.1) | −41.8 (−26.6 to −88.5) | 0.155 |
| Never smoker | −41.6 (−3.4 to −77.7) | −33.6 (−11.9 to −66.9) | 0.542 |
| COPD | −38.2 (−9.2 to −76.1) | −52.3 (−24.4 to −94.3) | 0.818 |
| No COPD | −34.7 (−7.5 to −71.8) | −35.1 (−13.6 to −67.8). | 0.120 |
| Lung index case | −38.1 (−8.6 to −85.2) | −41.8 (−19.7 to −85.4) | 0.278 |
| Non-lung index case | −38.1 (−7.9 to −82.4) | −36.5 (−14.2 to −67.7) | 0.879 |