Comparison of sweat chloride and NPD outcomes
| NPD | ||||
|---|---|---|---|---|
| Normal (n=97) | Borderline (n=38) | Abnormal (n=67) | ||
| Normal (n=121) | 73 (60%) | 24 (20%) | 24 (20%) | |
| Sweat chloride | Borderline (n=46) | 17 (37%) | 10 (22%) | 19 (41%) |
| Abnormal (n=35) | 7 (20%)* | 4 (11%) | 24 (69%)† | |
*The seven subjects include one RESP, one PANC and five AZOOSP.
†14/24 (58%) were not identified with two CF-causing mutations: 12 carried one CF-causing mutation (DF508/−(x5); DF508/5 T (x3); DF508/D1152H; R75X/V456A; 1717-1G>A/Q1291H; 1717-1G>A/5 T) and two had no CF-causing mutation (D579G/D579G; −/−).
AZOOSP, obstructive azoospermia; CF, cystic fibrosis; NPD, nasal potential difference; PANC, chronic/recurrent pancreatitis; RESP, chronic sino-pulmonary disease.