Healthy (n=8) | Subjects with asthma (n=26) | |
---|---|---|
Subject demographics | ||
Age years (±SD) | 34 (11) | 35 (11) |
Male/Female | 4/4 | 12/14 |
BMI kg/m2 (±SD) | 23 (3) | 25 (5) |
Pulmonary function tests | ||
FEV1%pred (±SD) | 102 (10) | 84 (15) |
FVC %pred (±SD) | 103 (10) | 93 (11) |
FEV1/FVC % (±SD) | 81 (6) | 74 (11) |
sRaw cmH2O·s (±SD) | 3.0 (0.5) | 6.9 (4.7) |
FeNO ppb (±SD) | 18* | 44 (45) |
PC20 mg/mL (±SD) | 42.3 (19.2) | 5.9 (12.3) |
Dyspnoea scores | ||
mMRC score (±SD) | 0 (0) | 1 (1) |
Borg score (±SD) | 0 (0) | 0.5 (1) |
*n=1.
%pred, per cent predicted; BMI, body mass index; FeNO, fraction of exhaled nitric oxide; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; mMRC, modified Medical Research Council; PC20, provocative concentration of methacholine sufficient to induce a 20% decrease in FEV1; sRaw, specific airways resistance.