Table 1

Summary of significant correlations*

Correlate 1Correlate 2Pearson correlation coefficient (r)Significance (p)n
Significant patient-specific pairwise correlations
 Clinical: clinical correlations
  FEV1Temperature0.5390.04714
  FEV6No. CFPEs−0.5730.03214
  No. CFPEsAge−0.5330.0514
  GenotypeAge0.6520.01214
  PRO sumGender0.7580.002*14
  BMINebulised colomycin0.6210.01814
 Clinical: microbiological correlations
  FEV6Rank abundance slope−0.6020.02314
  FEV6Species number0.5490.04214
 Microbiological: microbiological correlations
  Pseudomonas aeruginosa T-RF %Rank abundance slope−0.7630.002*14
  P aeruginosa T-RF %Species number−0.7630.002*14
  P aeruginosa T-RF %Bray-curtis similarity−0.7150.00414
  Species numberRank abundance slope−0.7110.00414
Significant patient independent pairwise correlations across all samples
 FEV1Species number0.7710.0001168
 FEV6Species number0.7480.0001168
 FEV1Rank abundance slope−0.6720.0001168
 FEV6Rank abundance slope−0.7120.0001168
 FEV1P aeruginosa T-RF %−0.7060.0001168
 FEV6P aeruginosa T-RF %−0.6910.0001168
  • * Correlations for which p<0.05 after Bonferroni correction.

  • BMI, body mass index; CFPE, cystic fibrosis pulmonary exacerbation; FEV1, forced expiratory volume in 1 s; FEV6, forced expiratory volume in 6 s; PRO, patient-reported outcome; T-RF, terminal restriction fragment.