Table 1

Characteristics of study groups

StatusHCPPPAP APA+X
N10101010104
Age (years)29.7±7.229.7±529±4.326.5±7.927.4±6.131.2±4.9
Gestational age (weeks)NA26.2±2.1NANA25.1±1.931.3±4.9
ACQNANANA0.71 (0.71)0.35 (0.72)1.94 (0.95*)
%FEV1109.6±11.8101.4±8.598.7±9.792.8±9.1*88.2±11.1*75.5±21.9*
Blood IgE (IU/ml)nd39.5 (47)39 (117)nd289 (384)*200.5 (246.5)*
ICS use (n)NANANA253
ICS daily dose (μg/day BUD equivalent)NANANA0 (500)200 (800)400 (800)
  • Parametric data represented as mean±SD, non-parametric data as median (IQR).

  • ACQ, a measure of asthma control based on the asthma control questionnaire, where an ACQ score of >1.5 is considered to be uncontrolled asthma; %FEV1, forced expiratory volume in 1 s as per cent predicted; Blood IgE, total allergy score; IU, international units; ICS use, number of women on inhaled corticosteroids at the time of sample collection; ICS daily dose, total µg/day of budesonide (BUD) equivalents. Asthmatics were currently on budesonide-eformoterol (Symbicort), budesonide or fluticasone-salmeterol (Seretide), where 0.5 µg fluticasone propionate=1 µg budesonide; nd, no data were collected; NA, not applicable; HC, healthy control (non-pregnant, non-asthmatic); P, pregnant; PP, post partum; A, asthma; PA, pregnant asthmatic; PA+X, pregnant asthmatic with current asthma exacerbation.

  • *p<0.001.