Table 2

Differences between healthy control and allergic asthmatic groups after air exposure

ParameterHealthyAsthmaticsUnitsp Value
BW total cells9.2 (5.7–10.0)8.2 (6.6–10.8)Cells/ml×104NS
BW neutrophil0.85 (0.44–1.52)0.85 (0.43–1.17)Cells/ml×104NS
SM neutrophil62 (31–78)82 (32–108)Cells/mm2NS
BW lymphocyte0.23 (0.08–0.33)0.14 (0.06–0.35)Cells/ml×104NS
SM CD3+42 (24–58)34 (17–77)Cells/mm2NS
BW eosinophil0.01 (0–0.04)0.05 (0.01–0.12)Cells/ml×1040.013
SM eosinophil0.000 (0–0)0.00 (0–0.61)Cells/mm20.021
BW mast cell0.000 (0–0.003)0.005 (0.002–0.016)Cells/ml×104<0.001
SM mast cell19 (11–27)22 (13–28)Cells/mm2NS
BW IL-63.2 (1.6–4.9)3.1 (2.1–4.6)pg/mlNS
BW IL-847 (20–95)32 (22–81)pg/mlNS
BW MPO4.9 (3.1–9.4)6.5 (4.0–13.8)μg/lNS
BW SCF16.8 (13.8–19.5)15.2 (13.4–17.5)pg/mlNS
ICAM-169 (57–89)69 (52–93)% of total EN4 stainingNS
VCAM-15.6 (2.5–9.8)2.6 (0.6–5.9)% of total EN4 staining0.023
  • Data are presented as median and IQR.

  • BW, bronchial wash; CD3+, T lymphocytes; ICAM, intracellular adhesion molecule; IL, interleukin; MPO, myeloperoxidase; NS, non-significant; SCF, stem cell factor; SM, bronchial biopsy submucosa; VCAM, vascular cell adhesion molecule.