Characteristics of participants included in the study
| COPD (n=24) | Controls (n=8) | p Value | |
|---|---|---|---|
| Age | 66.0 (12.0) | 56.0 (18.0) | 0.064 |
| Male | 16 | 6 | >0.999 |
| Current smoker | 11 | 5 | 0.685 |
| FEV1% | 69.00 (21.00) | 108.00 (20.25) | <0.001* |
| FEV1/FVC | 54.50 (10.75) | 78.00 (9.50) | <0.001* |
| FEF25%–75% | 21.50 (16.0) | 77.50 (45.25) | <0.001* |
| Emphysema % (%LAA) | 8.24 (7.17) | 2.55 (3.35) | 0.029* |
| Bronchial wall area (Pi10) | 3.74 (0.15) | 3.74 (0.04) | 0.502 |
| Small airways disease (E/I MLD) | 0.86 (0.08) | 0.76 (0.10) | 0.002* |
Values are given as medians (IQR).
Male and current smokers given as number of subjects.
%LAA and Pi10 given for 31 subjects. The ratio of mean lung density in expiration to inspiration (E/I MLD) is given for a subcohort of 22 subjects who had expiratory CT scans.
Fisher's exact test for male and current smoker. Mann–Whitney U test for all other variables.
*p<0.05.