Demographic details of the OPCRD cohorts (for list of steroid-induced morbidities see online supplementary table E1)
| Demographics | All (n=7195) | Severe asthma (n=808) | Mild/moderate asthma (n=3975) | Non-asthma controls (n=2412) | p Value |
|---|---|---|---|---|---|
| Female, n (%) | 4503 (63) | 507 (63) | 2515 (63) | 1481 (61) | – |
| Age (years)* | 58±17 | 59±17 | 58±16 | 58±17 | – |
| Geographical region, n (%) | |||||
| London | 597 (8) | 55 (7) | 344 (9) | 198 (8) | 0.06 |
| South of England | 903 (13) | 93 (12) | 477 (12) | 333 (14) | |
| East of England | 1064 (15) | 115 (14) | 616 (15) | 333 (14) | |
| Midlands | 2146 (30) | 248 (31) | 1213 (31) | 685 (28) | |
| North of England | 1648 (23) | 193 (24) | 874 (22) | 581 (24) | |
| Scotland/NI/Wales/unknown | 837 (12) | 104 (13) | 451 (11) | 282 (12) | |
| Number of corticosteroid-related comorbidities† n (%) | |||||
| 0 | 1790 (25) | 60 (7) | 866 (22) | 864 (36) | <0.001 |
| 1 | 1754 (24) | 136 (17) | 1044 (26) | 574 (24) | |
| 2 | 1382 (19) | 181 (22) | 797 (20) | 404 (17) | |
| ≥3 | 2269 (32) | 431 (53) | 1268 (32) | 570 (24) | |
p Values are not provided for age/gender as cohorts were matched based on age/gender.
*Mean±SD.
†See online supplementary table E1 for morbidities examined.
OPCRD, Optimum Patient Care Research Database.