Body mass index (kg/m2) | Allele score | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
<18.5 (n=705) | 18.5–22.4 (n=14 842) | 22.5–24.9 (n=21 713) | 25–27.4 (n=20 581) | 27.5–29.9 (n=13 724) | 30–34.9 (n=10 783) | 35–39.9 (n=2397) | ≥40 (n=692) | p for trend* | p for trend* | |
Age (years) | 58 (46–68) | 54 (45–65) | 57 (47–66) | 59 (49–68) | 60 (50–68) | 60 (51–68) | 59 (49–67) | 57 (48–65) | 8×10−212 | 0.98 |
Men (%) | 12 | 23 | 42 | 55 | 57 | 52 | 38 | 30 | <1×10−300 | 0.91 |
Familial predisposition for asthma (%) | 14 | 18 | 17 | 17 | 18 | 19 | 20 | 22 | 1×10−8 | 0.004‡ |
Ever-smokers (%) | 55 | 53 | 57 | 60 | 61 | 61 | 61 | 57 | 2×10−43 | 0.004‡ |
Cumulative tobacco consumption (pack-years)† | 20 (7–33) | 12 (4–25) | 14 (5–28) | 16 (7–30) | 20 (8–34) | 21 (10–36) | 20 (9–37) | 19 (7–35) | 6×10−247 | 0.03‡ |
Low level of education (%) | 21 | 17 | 21 | 26 | 32 | 37 | 38 | 37 | <1×10−300 | 0.09 |
Low annual household income (%) | 19 | 11 | 11 | 12 | 14 | 17 | 20 | 21 | 7×10−77 | 0.10 |
Low physical activity in leisure time (%) | 7 | 4 | 4 | 5 | 7 | 10 | 18 | 25 | 2×10−248 | 0.34 |
Low physical activity during work (%) | 26 | 32 | 32 | 30 | 28 | 25 | 25 | 28 | 3×10−51 | 0.14 |
Low physical activity in leisure time and during work (%) | 32 | 24 | 25 | 27 | 31 | 36 | 42 | 47 | 1×10−180 | 0.74 |
Weekly intake of fast food (%) | 22 | 24 | 24 | 25 | 25 | 25 | 26 | 32 | 0.001 | 0.95 |
Low intake of fruits (%) | 30 | 24 | 26 | 29 | 32 | 32 | 32 | 28 | 8×10−63 | 0.08 |
Low intake of vegetables (%) | 29 | 23 | 26 | 31 | 35 | 39 | 40 | 40 | 1×10−250 | 0.07 |
Low intake of fruits and vegetables (%) | 17 | 12 | 14 | 17 | 19 | 21 | 22 | 20 | 5×10−112 | 0.03‡ |
Data are summarised as median with the 25th and 75th centiles, or per cent.
*p Values were calculated using Cuzick’s non-parametrical trend test across ordered groups.
†Only current and former smokers were included.
‡p Value non-significant when adjusted for number of individual trend analyses according to the Bonferroni method.