UMEC (62.5mcg) N = 89 | VI (25mcg) N = 140 | UMEC/VI (62.5/25mcg) N = 282 | Placebo N = 321 | |
Baseline EET, seconds (SD) | 297.1 (159.4) | 303.5 (130.4) | 307.7 (162.6) | 328.1 (182.1) |
Day 2 | ||||
LS mean change from baseline EET, seconds (SE) | 36.4 (13.7) | 37.5 (11.1) | 66.8 (7.9) | 13.8 (7.4) |
LS mean change from baseline EET,% (SE) | 15.7 (5.8) | 14.9 (4.7) | 26.5 (3.3) | 8.1 (3.1) |
Day 84 | ||||
LS mean change from baseline EET, seconds (SE) | 44.6 (18.9) | 27.9 (15.5) | 62.9 (10.8) | 19.2 (10.4) |
LS mean change from baseline EET,% (SE) | 20.4 (7.7) | 12.6 (6.3) | 27.3 (4.4) | 10.9 (4.2) |