Baseline characteristics of the total sample and stratified by quartiles of gait speed
| Quartiles of gait speed | ||||||
|---|---|---|---|---|---|---|
| Baseline characteristic | Total population All (n=213) | Q1 <0.40 m/s (n=54) | Q2 0.40–0.59 m/s (n=53) | Q3 0.60–0.79 m/s (n=54) | Q4 ≥0.80 m/s (n=52) | p Value |
| Age (years) | 72.1 (10.8) | 76.2 (9.8) | 76.5 (9.0) | 69.2 (10.1) | 66.0 (10.7) | <0.001 |
| Male, n (%) | 111 (52.1) | 25 (46.3) | 25 (47.2) | 27 (50.0) | 34 (65.4) | 0.170 |
| Smoking pack year history | 44 (30) | 46 (32) | 43 (33) | 47 (26) | 39 (29) | 0.510 |
| Lives alone | 91 (42.7) | 28 (54.9) | 23 (42.6) | 25 (46.3) | 15 (27.8) | 0.040 |
| BMI (kg/m2) | 25.6 (22.1, 29.6) | 26.1 (21.7, 31.3) | 25.4 (20.7, 30.0) | 25.5 (21.9, 29.9) | 25.5 (23.3, 28.2) | 0.771 |
| FEV1% pred. | 35 (26, 49) | 41 (30, 52) | 30 (24, 43) | 36 (22, 54) | 35 (26, 48) | 0.085 |
| One or more admissions in last year, n (%) | 79 (37.1) | 18 (33.3) | 20 (37.7) | 18 (33.3) | 23 (44.2) | 0.615 |
| Number of exacerbations in previous year | 2 (1, 4) | 3 (1, 4) | 1.5 (0.75, 4) | 2 (1, 4) | 2 (1, 4) | 0.544 |
| Length of stay (days) | 3 (1, 5) | 4 (2, 5) | 3 (2, 6) | 2 (1, 4) | 1 (1, 3) | <0.001 |
| DECAF | 1 (1, 2) | 2 (1, 3) | 2 (1, 3) | 1 (1, 2) | 1 (0, 2) | <0.001 |
| Total number of comorbidities | 3 (2, 5) | 4 (3, 5) | 3 (2, 4) | 3 (2, 4) | 2 (1, 3) | <0.001 |
| Charlson Index | 1 (1, 2) | 2 (1, 4) | 2 (1, 3) | 2 (1, 3) | 1 (1, 2) | 0.005 |
| MRC 1–3 | 65 (30.5) | 8 (14.8) | 13 (24.5) | 16 (29.6) | 28 (53.9) | <0.001 |
| MRC 4 | 42 (19.7) | 6 (11.1) | 8 (15.1) | 15 (27.8) | 13 (25.0) | |
| MRC 5 | 106 (49.8) | 40 (74.1) | 32 (60.4) | 23 (42.6) | 11 (21.2) | |
| SGRQ total | 56.7 (16.5) | 65.2 (13.3) | 57.5 (16.6) | 56.5 (15.2) | 47.4 (15.9) | <0.001 |
| Katz Index | ||||||
| 1–4 | 18 (8.5) | 11 (20.4) | 4 (7.7) | 3 (5.6) | 0 (0.0) | 0.001 |
| 5–6 | 194 (91.5) | 43 (79.6) | 48 (92.3) | 51 (94.4) | 52 (100.0) | |
| Daily energy expenditure (kcal/day) | 68 (11, 141) | 11 (0, 90) | 51 (7, 96) | 63 (22, 185) | 124 (70, 268) | <0.001 |
| 4MGS, m/s | 0.61 (0.26) | 0.28 (0.10) | 0.50 (0.05) | 0.69 (0.60) | 0.95 (0.15) | <0.001 |
Data expressed as mean (SD) or median (25th, 75th centiles).
4MGS, 4 m gait speed; BMI, body mass index; DECAF score, extended MRC Dyspnoea Score, Eosinopenia, Consolidation, Acidaemia, atrial Fibrillation; MRC, Medical Research Council Dyspnoea Score; SGRQ, St George's Respiratory Questionnaire.