Diagnostic accuracy of PM-AHIs for AHI thresholds of ≥5/h, ≥15/h and ≥30/h in high-risk subjects
| Sens (%) | Spe (%) | PPV (%) | NPV (%) | LR+ | PPTP (%) | LR− | NPTP (%) | CC (%) | |
|---|---|---|---|---|---|---|---|---|---|
| AHI ≥5/h (n=93; pre-test probability=80.17%) | |||||||||
| PM-AHI1 | 98.92 | 86.96 | 96.84 | 95.24 | 7.58 | 96.84 | 0.01 | 3.89 | 96.55 |
| PM-AHI2 | 100.00 | 26.09 | 84.55 | 100.00 | 1.35 | 84.52 | 0.00 | 0.00 | 85.34 |
| PM-AHI3 | 81.72 | 100.00 | 100.00 | 57.50 | * | 100.00 | 0.18 | 42.12 | 85.34 |
| PM-AHI4 | 100.00 | 47.83 | 88.57 | 100.00 | 1.92 | 88.59 | 0.00 | 0.00 | 89.66 |
| AHI ≥15/h (n=63; pre-test probability=54.31%) | |||||||||
| PM-AHI1 | 95.24 | 92.45 | 93.75 | 94.23 | 12.62 | 93.75 | 0.05 | 5.61 | 93.97 |
| PM-AHI2 | 100.00 | 64.15 | 76.83 | 100.00 | 2.79 | 76.83 | 0.00 | 0.00 | 83.62 |
| PM-AHI3 | 58.73 | 100.00 | 100.00 | 67.09 | * | 100.00 | 0.41 | 32.77 | 77.59 |
| PM-AHI4 | 80.95 | 98.11 | 98.08 | 81.25 | 42.90 | 98.08 | 0.19 | 18.42 | 88.79 |
| AHI ≥30/h (n=32; pre-test probability=27.59%) | |||||||||
| PM-AHI1 | 81.25 | 100.00 | 100.00 | 93.33 | * | 100.00 | 0.19 | 6.75 | 94.83 |
| PM-AHI2 | 96.88 | 95.24 | 88.57 | 98.77 | 20.34 | 88.57 | 0.03 | 1.13 | 95.69 |
| PM-AHI3 | 37.50 | 100.00 | 100.00 | 80.77 | * | 100.00 | 0.63 | 19.36 | 82.76 |
| PM-AHI4 | 62.50 | 98.81 | 95.24 | 87.37 | 52.50 | 95.24 | 0.38 | 12.65 | 88.79 |
*Infinite value.
AHI, apnoea–hypopnoea index; CC, correctly classified; −LR, negative likelihood ratio; +LR, positive likelihood ratio; NPTP, negative post-test probability; NPV, negative predictive value; PM-AHI, portable monitors apnoea–hypopnoea index; PPTP, positive post-test probability; PPV, positive predictive value; Sens, sensitivity; Spe, specificity.