Table 3

Markers of systemic inflammation

	NBS+A				BS+A				BS−A
	Baseline	6-month FU	12-month FU	p Value*	Baseline	6-month FU	12-month FU	p Value*	Baseline	6-month FU	12-month FU	p Value*
hs-CRP (ng/mL)	34.4 (1.3–142.0)	49.8 (20.0–142.0)	32.6 (8.5–142.0)	0.953	36.0 (4.3–142.0)	10.1 (1.8–75.6)	7.1 (0.8–139.5)	<0.001	30.4 (0.1–87.0)	13.8 (0.1–51.5)	5.3 (0.8–35.2)	<0.001
IL-6 (pg/mL)	0.7 (0.7–0.9)	0.7 (0.7–6.3)	0.7 (0.7–7.6)	0.655	0.7 (0.7–2.1)	0.7 (0.7–6.9)	0.7 (0.7–5.1)	0.211	0.7 (0.7–13.3)	0.7 (0.7–1.1)	0.7 (0.7–0.8)	0.017
IL-8 (pg/mL)	4.1 (3.0–6.6)	3.9 (1.9–7.3)	4.8 (1.8–8.7)	0.799	3.9 (2.7–13.5)	4.3 (2.4–10.0)	4.8 (1.2–13.3)	0.124	4.0 (1.9–9.1)	4.2 (0.7–7.5)	3.8 (2.1–7.8)	0.225
TNFα (pg/mL)	0.8 (0.8–0.8)	0.8 (0.8–2.8)	0.8 (0.8–2.9)	0.180	0.8 (0.8–1.3)	0.8 (0.8–3.0)	0.8 (0.8–2.4)	0.715	0.8 (0.8–1.0)	0.8 (0.8–1.5)	0.8 (0.8–0.8)	0.180
GM-CSF (pg/mL)	0.6 (0.6–1.7)	0.6 (0.6–26.8)	0.6 (0.6–9.4)	0.686	0.6 (0.6–3.9)	0.6 (0.6–11.5)	0.6 (0.6–3.5)	0.401	0.6 (0.6–0.6)	0.6 (0.6–0.9)	0.6 (0.6–1.5)	0.180
Adiponectin (ng/mL)	10.4 (7.0–17.7)	14.3 (5.9–246.9)	11.2 (5.7–235.6)	0.241	12.0 (4.5–22.0)	17.0 (8.8–1000.0)	22.5 (9.7–1000.0)	<0.001	14.1 (0.06–28.9)	17.6 (7.8–31.9)	23.3 (5.2–40.0)	<0.001
Leptin (ng/mL)	42 (2–97)	54 (4–100)	54 (3–86)	0.721	69 (18–100)	18 (2–98)	11 (0.2–69)	<0.001	55 (11–100)	7 (0.7–43)	6 (0.2–68)	<0.001

Data are presented as median (min–max).
*p Value for comparison baseline versus 12-month follow-up within each group (related samples Wilcoxon signed rank test).
BS+A, bariatric surgery and asthma group; BS−A, bariatric surgery without asthma group; FU, follow-up; GM-CSF, granulocyte macrophage colony-stimulating factor; hs-CRP, high-sensitivity C-reactive protein; IL, interleukin; NBS+A, no bariatric surgery and asthma group; TNF, tumour necrosis factor.