Within-group comparison and between-group comparison for cytokine levels and total IgE in patients with asthma
| Control group (n=21) | Training group (n=22) | Treatment effect | ||||||
|---|---|---|---|---|---|---|---|---|
| Outcomes | Before | Mean (95% CI) within-group difference | p Value time | Before | Mean (95% CI) within-group difference | p Value time | Mean (95% CI) between-group difference | p Value treatment |
| IL-5 (fg/mL) | 129.2 (80.1 to 205.3) | 46.8 (−3.3 to 95.6) | 0.066 | 155.5 (87.4, −170.3) | 2.0 (−21.2 to 25.1) | 0.862 | −19.4 (−53.3 to 14.4) | 0.252 |
| IL-6 (fg/mL) | 298.2 (162.8 to 633.9) | 67.6 (−186.7 to 322.0) | 0.585 | 258.7 (214.5 to 467.6) | 212.6 (83.0 to 341.7) | 0.003 | 207.1 (7.7 to 406.1) | 0.042 |
| IL-8 (fg/mL) | 1713.9 (1392 to 1858) | 51.7 (−185.9 to 289.6) | 0.655 | 1564.0 (1115 to 1941) | 318.8 (76.0 to 561.6) | 0.013 | 127.3 (−5.4 to 508.6) | 0.055 |
| IL-10 (fg/mL) | 100.7 (1.0 to 166.7) | 21.3 (−16.4 to 58.9) | 0.253 | 95.4 (1.0 to 123.9) | 17.6 (−16.3 to 51.5) | 0.291 | 10.7 (−39.1 to 60.5) | 0.667 |
| MCP-1 (pg/mL) | 14.1 (4.5 to 19.3) | 0.5 (−2.8 to 3.9) | 0.743 | 20.6 (17.1 to 26.7) | 4.5 (−0.4 to 9.0) | 0.052 | −5.3 (−10.5 to −0.1) | 0.045 |
| IgE (IU/mL) | 289.0 (60.5 to 878.5) | 65.4 (−133.3 to 264.1) | 0.500 | 360.5 (78.5 to 993.2) | −238.5 (−1066.3 to 589.4) | 0.555 | −280.4 (−1144 to 583.7) | 0.516 |
Values are presented as medians and (25th–75th) percentiles.fg, femtogram; IgE, immunoglobulin E; IL, interleukin; MCP-1, monocyte chemotactic protein 1; pg, picogram.