Univariate analysis of predictors of postoperative ARDS in patients undergoing oesophagectomy
| Patients with ARDS (n=15) | Patients without ARDS (n=50) | p Value | |
|---|---|---|---|
| Male, n (%) | 14 (93) | 43 (86) | 0.448 |
| Age (years), median (IQR) | 61 (53–66) | 66 (56–71) | 0.304 |
| BMI (kg/cm2), median (IQR) | 25.2 (23.9–29.1) | 24.8 (21.6–28.1) | 0.460 |
| FEV1 (L), median (IQR) | 2.69 (2.28–3.50) | 2.85 (2.38–3.3) | 0.901 |
| FVC (L), median (IQR) | 4.3 (3.4–5.2) | 4.1 (3.5–4.7) | 0.450 |
| Tumour type=adenocarcinoma, n (%) | 12 (80) | 35 (70) | 0.511 |
| Tumour stage, n (%)* | |||
| T2 | 4 (27) | 12 (24) | 0.865 |
| T3 | 11 (73) | 37 (76) | |
| N0 | 3 (20) | 12 (24) | 0.719 |
| N1–2 | 12 (80) | 37 (76) | |
| Smoker, n (%) | |||
| Current | 6 (40) | 11 (22) | 0.304 |
| Former | 7 (47) | 34 (68) | |
| Never | 2 (13) | 5 (10) | |
| Pack-years, median (IQR) | 30 (20–40) | 30 (15–45) | 0.740 |
| Plasma 25-OH vitamin D3 (nmol/L), Median (IQR) | 16.97 (12.98–22.46) | 25.46 (17.35–39.77) | 0.014 |
| Plasma 1,25(OH)2 vitamin D (pmol/L), median (IQR) | 68 (47–91) | 89 (76–109) | 0.007 |
Only preoperative 25(OH)D3 and 1,25(OH)2D vitamin D were significantly different in univariate analysis.
*No lung function available for seven patients, pack-years not available for two patients. One patient (without lung injury) had a benign tumour—not included in staging data.
ARDS, acute respiratory distress syndrome; BMI, body mass index.